Table 3 Risk of outcomes by mode of delivery (RCB vs. VBAC) from selected Sites (Guatemala, Belagavi, Nagpur, Pakistan and Bangladesh) of global network for Women’s and Children’s health research, maternal and newborn health registry
Characteristics | Women with a history of cesarean birth | VBAC | RCB | P-value* | Adjusted** P-value | Adjusted** RR (95% C.I.) |
|---|---|---|---|---|---|---|
Mothers, N | 8,267 | 1,389 | 6,878 | |||
Severe postpartum hemorrhage, n (%) | 80/8,259 (1.0) | 19/1,389 (1.4) | 61/6,870 (0.9) | 0.0577 | 0.0683 | 0.55 (0.29, 1.05) |
Uterotonics, n (%) | 6,685/8,237 (81.2) | 845/1,388 (60.9) | 5,840/6,849 (85.3) | 0.0003 | 0.2384 | 1.07 (0.96, 1.19) |
Blood transfusion, n (%) | 602/8,266 (7.3) | 21/1,389 (1.5) | 581/6,877 (8.4) | < .0001 | < .0001 | 3.74 (2.48, 5.63) |
D&C or suction, n (%) | 47/8,265 (0.6) | 33/1,389 (2.4) | 14/6,876 (0.2) | < .0001 | < .0001 | 0.12 (0.06, 0.25) |
Magnesium Sulfate, n (%) | 205/8,232 (2.5) | 7/1,388 (0.5) | 198/6,844 (2.9) | 0.0304 | 0.0748 | 1.93 (0.94, 3.99) |
Hysterectomy, n (%) | 28/8,265 (0.3) | 1/1,389 (0.1) | 27/6,876 (0.4) | 0.1000 | 0.0757 | 10.54 (0.78, 141.70) |
Severe perinatal infection, n (%) | 112/8,266 (1.4) | 18/1,389 (1.3) | 94/6,877 (1.4) | 0.7226 | 0.9015 | 1.03 (0.64, 1.66) |
Severe postnatal infection/sepsis, n (%) | 37/8,258 (0.4) | 3/1,386 (0.2) | 34/6,872 (0.5) | 0.2291 | 0.1058 | 2.79 (0.80, 9.70) |
Seizures/coma, n (%) | 15/8,258 (0.2) | 0/1,386 (0.0) | 15/6,872 (0.2) | *** | *** | *** |
Unplanned hospitalization, n (%) | 776/8,265 (9.4) | 97/1,389 (7.0) | 679/6,876 (9.9) | 0.0272 | 0.9359 | 0.99 (0.79, 1.24) |
Maternal death < 42 days, rate per 100,000 births | 9 (109) | 4 (288) | 5 (73) | 0.0301 | *** | *** |
Infants, N | 8,335 | 1,398 | 6,937 | |||
Stillbirths, rate per 1,000 stillbirths plus live births | 176 (21.1) | 100 (72.0) | 76 (11.0) | < .0001 | < .0001 | 0.27 (0.15, 0.49) |
Bag and mask resuscitation | 395/8,298 (4.8) | 60/1,372 (4.4) | 335/6,926 (4.8) | 0.6114 | 0.8938 | 1.02 (0.72, 1.45) |
Baby breastfed within an hour | 2,699/8,148 (33.1) | 926/1,289 (71.8) | 1,773/6,859 (25.8) | < .0001 | < .0001 | 0.39 (0.30, 0.50) |
Antibiotics | 716/8,308 (8.6) | 73/1,377 (5.3) | 643/6,931 (9.3) | 0.0003 | 0.0005 | 1.51 (1.20, 1.91) |
CPAP | 44/8,301 (0.5) | 5/1,375 (0.4) | 39/6,926 (0.6) | 0.3936 | *** | *** |
Oxygen | 647/8,306 (7.8) | 75/1,378 (5.4) | 572/6,928 (8.3) | 0.0027 | 0.0319 | 1.31 (1.02, 1.67) |
Neonatal mortality < 28 days, rate per 1,000 live births | 185 (22.7) | 54 (42.0) | 131 (19.1) | < .0001 | 0.4734 | 0.86 (0.57, 1.30) |