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Table 1 Causes of stillbirth, neonatal death and maternal death and their hierarchical position in the Global Network Classification System

From: Global network for women’s and children’s health research: a system for low-resource areas to determine probable causes of stillbirth, neonatal, and maternal death

 

Comment

Stillbirth

 

Maternal or fetal trauma

Significant maternal trauma especially if the maternal abdomen is involved or there is evidence of fetal trauma takes precedence as a cause of stillbirth over all other potential causes

Major Congenital anomaly

Major anomaly takes presedence as a cause of death over all other conditions except trauma

Maternal infection

Maternal malaria or syphilis or signs of amnionitis

Asphyxia

Based on the maternal or fetal condition noted including obstructed labor, abruption or previa characterized by antepartum bleeding, preeclampsia/eclampsia, fetal distress and cord complications

Complications of preterm labor

There are some early gestational age stillbirths, generally prior to 24 weeks, where the fetus apparently dies because it is unable to tolerate labor. These very preterm babies are usually not macerated since they usually have died close to delivery

Unknown

No other cause identified

Neonatal death

 

Major Congenital anomaly

Significant congenital anomaly takes precedence as a cause of neonatal death

Sepsis/pneumonia/tetanus

The presence of these conditions take precedence as a cause of death except when an anomaly is present

Asphyxia

Breathing difficulties at birth with maternal condition noted including obstructed labor, bleeding, preeclampsia/eclampsia, fetal distress, cord complications, etc.

Complications of prematurity

Deaths in preterm infants not attributable to other causes. Since it is difficult to differentiate asphyxia from respiratory distress syndrome, we have arbitrarily assigned larger infants with respiratory distress to asphyxia and the smaller or earlier preterm infants to complications of prematurity.

Unknown

No other cause identified

Maternal Death

 

Significant maternal trauma

Trauma takes precedence as a cause of maternal death

Abortion/miscarriage/medical termination of pregnancy/ectopic pregnancy

If the subject has a history of abortion or is less than 20 weeks, whether she had hemorrhage, sepsis or other conditions, the cause of death is considered an abortion

Infection

If there is no trauma or an abortion, the presence of significant infection takes precedence as a cause of maternal death

Hemorrhage

The most commonly attributed cause of maternal death in most settings

Hypertensive disease of pregnancy

If mother has a seizure, eclampsia is considered the cause of death. If she has only preeclampsia, other causes may take precedence

Thromboembolism

With no other obvious cause and sudden onset of severe respiratory distress and chest pain, the cause of death will be attributed to thromboembolism

Medical condition coincident to pregnancy

If a medical condition such as cancer, cardiac disease, severe anemia, or diabetes is present and there is no other cause of death, the death will be attributed to a medical condition

Unknown

No other cause identified