Table 5 Results of 6 Meta-Analyses Comparing Glyburide to Insulin Therapy
From: Oral hypoglycemic agents: do the ends justify the means?
| Â | Dhulkotia 2010 [45] | Poolsup 2014 [59] | Balsells 2015 [35] | Zeng 2014 [49] | Jiang 2015 [34] | Moretti 2008 [44] |
|---|---|---|---|---|---|---|
Therapy efficacy Glyburide vs. Insulin | similar | dissimilar | dissimilar | similar | suitable | similar |
Macrosomia | similar | Increase O.R. 2.34 | Increase R.R. 2.62 | Increase R.R. 2.22 | Increase O.R 3,09 | similar |
LGA | similar | similar | similar | similar | n.a. | similar |
Neonatal hypoglycemia | similar | Increase O.R. 2.06 | Increase R.R.2.04 | Increase O.R. 1.98 | Increase R.R. 2.64 | similar |
Neonatal hyperbilirubinemia. | n.a. | similar | similar | n.a. | n.a. | n.a |
Preterm | n.a. | similar | similar | similar | similar | n.a. |
NICU admission | n.a. | similar | similar | similar | similar | similar |
Preeclampsia | n.a. | similar | similar | --- | similar | n.a. |
Cesarean delivery | similar | similar | similar | similar | similar | n.a. |