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Table 1 Distribution of organisms responsible for late-onset sepsis

From: Prevention and treatment of neonatal nosocomial infections

Organism VLBW infants NICHD NRN 1991–19931 VLBW infants NICHD NRN 1998–20002 VLBW infants NICHD NRN 2002–20083
Incidence of LOS 25 21 25
Gram-positive    
Staphylococcus coagulase-negative 55 48 53
Staphylococcus aureus 9 8 11
Enterococcus/Group D strep 5 3 4
Group B streptococcus 2 2 2
Other 2 9 7
Gram-negative    
Enterobacter 4 3 3
Escherichia coli 4 5 5
Klebsiella 4 4 4
Pseudomonas 2 3 2
Other 4 1 2
Fungi    
Candida albicans 5 6 5
Candida parapsilosis 2 4 2
Other 2 2 1
  1. Numbers are expressed in percentages
  2. Abbreviations NICHD NRN National Institutes of Child Health and Human Development Neonatal Research Network, VLBW Very low birth weight, birth weight ≤1500 g