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Table 1 Comparison of symptoms of symptomatic presentationa between Dengue, Zika and Chikungunya

From: A review of selected Arboviruses during pregnancy

Signs/Symptoms Dengue Zika Chikungunya
Fever Above 38 °C (4 to 7 days) No fever or subfebrile ≤38 °C (1 to 2 days) Above 38 °C (2 to 3 days)
Rash Appears from the 4th day 30–50% of the cases Appears on the 1st or 2nd day 90–100% of cases Appears on the 2nd or 5th day 50% of cases
Myalgia +++/+++ ++/+++ +/+++
Arthralgia +/+++ ++/+++ +++/+++
Conjunctivitis Rare 50–90% of cases 30%
Headache +++ ++ ++
Pruritus Slight Moderate/Intense Slight
Blood dyscrasia Moderate Absent Slight
Neurological impairment Rare More frequent than Dengue and Chikungunya Rare (predominant in neonates)
  1. aEstimated symptomatic presentation in 50% of Dengue virus, 20% of Zika virus and 80% of Chikungunya virus infection