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Table 2 Comparison between measured composition of OMM and data from a meta-analysis [15]

From: The fortification method relying on assumed human milk composition overestimates the actual energy and macronutrient intakes in very preterm infants

Postnatal day Measured energy (Kcal/100 mL) Reporte denergy (Kcal/100 mL) Measured protein (g/100 mL) Reported protein (g/100 mL) Measured fat (g/100 mL) Reported fat (g/100 mL) Measured carbohydrate (g/100 mL) Reported carbohydrate (g/100 mL)
Day 1–3 Mean (SD) N = 73 61.0 (14.00) N = 143 58.80 (7.91) N = 73 1.84** (0.53) N = 163 2.57 (1.44) N = 73 3.01* (1.15) N = 173 2.52 (0.98) N = 73 6.25 (1.52) N = 143 6.2 (0.92)
Day 4–7 Mean (SD) N = 96 64.5 (10.49) N = 96 67.9 (14.1) N = 96 1.89* (0.49) N = 44 2.11 (0.44) N = 96 3.34 (1.11) N = 110 3.31 (1.27) N = 96 6.34 (1.54) N = 87 6.17 (0.49)
Week 2 Mean (SD) N = 157 62.0** (11.75) N = 417 69.1 (10.1) N = 157 1.70** (0.50) N = 383 1.98 (0.68) N = 157 3.19 (1.00) N = 426 3.19 (1.04) N = 157 6.32** (1.93) N = 389 6.72 (0.46)
Week 3–4 Mean (SD) N = 203 63.9** (9.62) N = 481 70.87 (9.34) N = 203 1.61 (0.46) N = 528 1.6 (0.5) N = 203 3.32** (0.87) N = 485 3.83 (1.01) N = 203 6.53** (1.26) N = 464 7.05 (0.51)
Week 5–6 Mean (SD) N = 84 67.6** (7.92) N = 354 73.97 (9.1) N = 84 1.55* (0.60) N = 330 1.43 (0.25) N = 84 3.63* (1.00) N = 371 4.04 (0.91) N = 84 6.71** (1.42) N = 354 7.14 (0.36)
Week 7–9 Mean (SD) N = 42 64.4** (9.81) N = 239 74.24 (8.77) N = 42 1.18** (0.23) N = 223 1.34 (0.2) N = 42 3.63* (0.85) N = 236 4.21 (0.92) N = 42 6.40** (1.16) N = 235 7.13 (0.38)
  1. t test; * p < 0.001; ** p < 0.0001 Abbreviations: OMM own mother’s milk