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Table 2 Comparison between measured composition of OMM and data from a meta-analysis [15]

From: The fortification method relying on assumed human milk composition overestimates the actual energy and macronutrient intakes in very preterm infants

Postnatal day Measured energy (Kcal/100 mL) Reporte denergy (Kcal/100 mL) Measured protein (g/100 mL) Reported protein (g/100 mL) Measured fat (g/100 mL) Reported fat (g/100 mL) Measured carbohydrate (g/100 mL) Reported carbohydrate (g/100 mL)
Day 1–3
Mean (SD)
N = 73
61.0 (14.00)
N = 143
58.80 (7.91)
N = 73
1.84** (0.53)
N = 163
2.57 (1.44)
N = 73
3.01* (1.15)
N = 173
2.52 (0.98)
N = 73
6.25 (1.52)
N = 143
6.2 (0.92)
Day 4–7
Mean (SD)
N = 96
64.5 (10.49)
N = 96
67.9 (14.1)
N = 96
1.89* (0.49)
N = 44
2.11 (0.44)
N = 96
3.34 (1.11)
N = 110
3.31 (1.27)
N = 96
6.34 (1.54)
N = 87
6.17 (0.49)
Week 2
Mean (SD)
N = 157
62.0** (11.75)
N = 417
69.1 (10.1)
N = 157
1.70** (0.50)
N = 383
1.98 (0.68)
N = 157
3.19 (1.00)
N = 426
3.19 (1.04)
N = 157
6.32** (1.93)
N = 389
6.72 (0.46)
Week 3–4
Mean (SD)
N = 203
63.9** (9.62)
N = 481
70.87 (9.34)
N = 203
1.61 (0.46)
N = 528
1.6 (0.5)
N = 203
3.32** (0.87)
N = 485
3.83 (1.01)
N = 203
6.53** (1.26)
N = 464
7.05 (0.51)
Week 5–6
Mean (SD)
N = 84
67.6** (7.92)
N = 354
73.97 (9.1)
N = 84
1.55* (0.60)
N = 330
1.43 (0.25)
N = 84
3.63* (1.00)
N = 371
4.04 (0.91)
N = 84
6.71** (1.42)
N = 354
7.14 (0.36)
Week 7–9
Mean (SD)
N = 42
64.4** (9.81)
N = 239
74.24 (8.77)
N = 42
1.18** (0.23)
N = 223
1.34 (0.2)
N = 42
3.63* (0.85)
N = 236
4.21 (0.92)
N = 42
6.40** (1.16)
N = 235
7.13 (0.38)
  1. t test; * p < 0.001; ** p < 0.0001 Abbreviations: OMM own mother’s milk