Table 4 Associations between maternal infection and timing of maternal infection during pregnancy and inflammatory markers
From: Maternal infections during pregnancy and offspring midlife inflammation
CRP | IL-6 | IL-10 | TNF-α | ||||||
|---|---|---|---|---|---|---|---|---|---|
Cases | Crude Factor (95% CI) | Factor (95% CI)* | Crude Factor (95% CI) | Factor (95% CI)* | Crude Factor (95% CI) | Factor (95% CI)* | Crude Factor (95% CI) | Factor (95% CI)* | |
Infection during pregnancy | 392 | 0.93 (0.81,1.06) | 0.93 (0.81,1.06) | 0.92 (0.84,1.01) | 0.92 (0.85,1.01) | 0.91;(0.77,1.08) | 0.91 (0.77,1.08) | 0.99 (0.94,1.03) | 0.99 (0.94,1.04) |
Timing of infection | |||||||||
Never | 1313 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Trimester 1 | 55 | 1.04 (0.78,1.34) | 1.05 (0.80,1.38) | 0.88 (0.73,1.06) | 0.90 (0.74,1.07) | 0.95 (0.85,1.06) | 0.95 (0.66,1.36) | 0.95 (0.85,1.06) | 0.95 (0.85,1.06) |
Trimester 2 &/or 3 Trimester 1 & later in pregnancy | 317 20 | 0.90 (0.78,1.02) 0.90 (0.78,1.02) | 0.90 (0.79,1.03) 0.90 (0.78,1.02) | 0.92 (0.84,1.02) 0.90 (0.78,1.02) | 0.93 (0.84,1.02) 0.90 (0.78,1.02) | 0.99 (0.94,1.04) 0.90 (0.78,1.02) | 0.91 (0.76,1.09) 0.90 (0.78,1.02) | 0.99 (0.94,1.04) 0.90 (0.78,1.02) | 0.99 (0.94,1.04) 0.90 (0.78,1.02) |