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Table 4 Measurements from infants who were randomized to resuscitation with an intact cord (intervention) or after early cord clamping (control), only including those resuscitated with bag and mask

From: Intact cord resuscitation versus early cord clamping in the treatment of depressed newborn infants during the first 10 minutes of birth (Nepcord III) – a randomized clinical trial

  Cord Clamping Group, Mean (SD) Difference (95% CI) P-valuea
Intact cord > 3 min Early < 1 min)
Readings from pulse oximeter (n = 72) (n = 45)   
 Saturation at 1 min (%) 73.7 (8.8) 62.6 (5.0) 11.1 (8.2 to 13.9) <.001
 Saturation at 5 min (%) 85.6 (8.1) 76.1 (3.9) 9.4 (6.9 to 12.0) <.001
 Saturation at 10 min (%) 91.9 (7.9) 85.1 (2.8) 6.8 (4.4 to 9.3) <.001
 Heart rate at 1 min 106 (3) 115 (5) −10 (−11 to −8) <.001
 Heart rate at 5 min 124 (4) 134 (4) −10 (− 11 to −8) <.001
 Heart rate at 10 min 136 (2) 136 (2) 1 (0 to 2) .05
Apgar score (n = 74) (n = 48)   
 Apgar at 1 min 5.0 (1.1) 3.8 (1.1) 1.2 (0.8 to 1.6) < 0.001
 Apgar at 5 min 6.7 (0.9) 6.0 (1.3) 0.7 (0.3 to 1.1) 0.001
 Apgar at 10 min 9.2 (1.2) 8.3 (1.8) 0.9 (0.3 to 1.5) 0.005
Timed events, Median (interquartile range) (n = 74) (n = 48)   
 Time of start of resuscitation (sec) 48 (30 to 71) 43 (23 to 57)   . 06b
 Time of first cry/breath (sec) 38 (34 to 45) 48 (45 to 62)   <.001b
 Time of regular breathing (sec)c 78 (67 to 155) 356 (98 to 389)   <.001b
 Time to cord clamping (sec) 187 (42 to 195) 25 (11 to 40)   <.001 b
  1. aCalculated using an unpaired 2-tailed t test
  2. bCalculated using Mann Whitney U test
  3. cIntact cord group n = 72 and the early group n = 45