Effects of timing of umbilical cord clamping on preventing early infancy anemia in low-risk Japanese term infants with planned breastfeeding: a randomized controlled trial

Table 4 As-treated Analysis for Transcutaneous Hb at 4 months, Neonatal Jaundice and Polycythemia

	DCC		ECC		Relative risk (95% CI) / Mean difference (95% CI)		p value
Primary outcome
Spectrophotometric hemoglobin (SpHb) at 4 months
(n = 137/DCC = 72, ECC = 65)	12.4	(0.8)	12.3	(0.7)	0.1	[−0.18, 0.32]	0.59
Secondary outcome
Anemia (SpHb < 11.0 g/dl) (n = 137/DCC = 72, ECC = 65)	1	(1.4)	0	(0)	1.0	[0.96, 1.01]	1.00
Neonatal jaundice
Total serum bilirubin (TsB) (days 3-5) ^a (n = 132/DCC = 70, ECC = 62)	12.9	(3.4)	12.0	(3.5)	0.9	[−0.33, 2.08]	0.15
Over the excess level of transcutaneous bilirubin (TsB) ^b (n = 132/DCC = 70, ECC = 62)	7	(10.0)	4	(6.5)	1.6	[0.48, 5.04]	0.54
Phototherapy ^c (n = 133/DCC = 70, ECC = 63)	8	(11.4)	4	(6.3)	1.8	[0.57, 5.69]	0.38
Hematocrit
Hematocrit level (days 3-5) (%) ^a (n = 131/DCC = 69, ECC = 62)	57.0	(5.1)	52.4	(5.2)	4.6	[2.84, 6.41]	< 0.01*
High hematocrit (Hct≧65%) (n = 131/DCC = 69, ECC = 62)	3	(4.3)	2	(3.2)	0.7	[0.12, 4.54]	1.00

Data are presented as mean (SD) or n (%)
^a The highest value among blood sampling conducted during days 3-5 were used
^b Over the excess value are based on Standard of Imura (1985)
^c Two (DCC = 1, ECC = 1) received phototherapy before met to standard of phototherapy for preventively. One (ECC = 1) did not received phototherapy even over level of the standard of phototherapy
*p < .05

ISSN: 2054-958X