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Table 2 Weight delta z-scores from birth to subsequent age points by univariate linear regression analysisa

From: Antibiotic exposure and growth patterns in preterm, very low birth weight infants

  Weight Delta Z-score at Age of Evaluation
~ 36 weeks ~ 2 months ~ 4 months ~ 6 months ~ 12 months
No. of infants 161 151 134 136 129
Gestational age 0.274b 0.477b 0.446b 0.445b 0.479b
Mode of delivery 0.270b,c 0.177b,c 0.121 0.130 0.111
Multiple gestation 0.091 0.081 0.034 0.022 0.025
Sex −0.208d,e − 0.111 − 0.072 − 0.091 − 0.040
IUGR 0.052 0.194b 0.163 0.164 0.162
SGA 0.059 0.078 0.191b 0.247b 0.250b
CRIB-II score −0.206d −0.379d − 0.334d − 0.310d −0.321d
Antibiotic exposure (days of therapy [DOT]) −0.375b −0.295b − 0.151 −0.080 − 0.119
BPD −0.294d − 0.262d −0.195d − 0.127 −0.209d
PDA −0.138 −0.107 − 0.077 −0.053 − 0.112
NEC −0.174 − 0.023 0.051 0.069 0.035
Late-onset sepsis −0.074 −0.192d − 0.129 −0.052 − 0.075
TPN (total days) −0.397d − 0.356d −0.206d − 0.131 −0.127
Total days of NPO −0.367d −1.313d −0.177 − 0.092 −0.109
Caloric density (36 weeks, kcal/ounce) −0.024 0.066 0.022 0.018 0.006
  1. IUGR intrauterine growth restriction, SGA small for gestational age, CRIB Clinical Risk Index for Babies, BPD bronchopulmonary dysplasia, PDA patent ductus arteriosus, NEC necrotizing enterocolitis, TPN total parenteral nutrition, NPO nothing per oral
  2. aPearson correlation
  3. bPositive correlation, P < 0.05
  4. cPositive correlation with delivery by caesarean section
  5. dNegative correlation, P < 0.05
  6. eNegative correlation with male sex