Skip to main content

Table 1 Descriptive summary of the studies included in the review

From: Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis

Study Study Year Country Adverse outcomes found to be associated with HT HT cut point (°C) No. of VLBW infants No. (%) of infants with HT
Levi et al. [38] 1981 USA Mortality 36.0 71 53 (74.6%)
Neonatal Data Collection Group [33] 1993 Malaysia Mortality 36.0 824 280 (33.9%)
Malaysian VLBW group [34] 1997 Malaysia Mortality 36.0 868 288 (33.2%)
Laptook et al. [13] 2003 USA Mortality (28% increase per 1 °C decrease) and sepsis (11% increase per 1 °C decrease) 36.0 5277 2475 (46.9%)
Sodemann et al. [39] 2003 Guinea-Bissau Mortality 34.5 23 13 (56.5%)
Demirel et al. [35] 2006 Turkey BPD 36.0 106 32 (30.1%)
Miller et al. [6] 2007 USA Mortality, IVH, and sepsis 36.5 8782 4953 (56.4%)
Ogunlesi et al. [32] 2008 Nigeria Mortality 36.5 15 14 (93.3%)
Ting et al. [7] 2011 Canada Mortality, sepsis and adverse neurodevelopmental outcomes 36.5 2739 968 (35.3%)
Audeh et al. [24] 2011 Israel Non 35.5 271 100 (36.9%)
Lyu et al. [37] 2012 Canada Mortality, severe neurological injury, severe ROP, NEC, and BPD 36.5 9833 3516 (35.7%)
De Almeida et al. [20] 2012 Brazil Mortality 36.0 1764 900 (51.0%)
Guinsburg et al. [12] 2015 Brazil Unfavorable outcome (in-hospital mortality or survival with BPD, IVH III/IV, PVL and/or ROP) 36.0 2646 868 (32.8%)
Chang et al. [10] 2015 Taiwan Mortality and RDS 36.5 341 262 (76.8%)
Das et al. [36] 2016 USA Sepsis 36.0 174 16 (9.19%)
Caldas et al. [9] 2019 Brazil Mortality and NEC 36.5 4356 2339 (53.7%)
Ng’eny et al. [11] 2019 South Africa Mortality and metabolic acidosis 36.0 799 453 (56.7%)
Yu et al. [5] 2020 China Mortality, RDS, IVH, NEC, and sepsis 36.5 1247 1100 (88.2%)