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Table 2 Adjusted odds ratios and mean/beta coefficients for maternal cotinine categories and selected birth outcomes, Healthy Start (2010–2014)

From: Prenatal exposure to tobacco and adverse birth outcomes: effect modification by folate intake during pregnancy

aORs/aMeans for Selected Birth Outcomes *

 

Preterm Birth

Small-for-Gestational Age Birth

Neonatal Adiposity

 

no/nō

aOR (95%CI)

no/nō

aOR (95%CI)

n

Adj. Beta Coefficients (95% CIs)

Adj. Means (95% CIs)

Cotinine categories

 < 0.05 ng/mL (LOD, no exposure)

23/493

1.00 (Reference)

59/455

1.00 (Reference)

463

Reference

9.50 (8.91, 10.10)

 0.05-550 ng/mL (SHS)

4/139

0.45 (0.13, 1.58)

20/123

0.92 (0.46, 1.83)

132

-0.44 (-1.30, 0.41)

9.00 (8.24, 9.76)

 ≥ 550 ng/mL (Active Smoking)

3/39

1.29 (0.33, 5.10)

20/22

6.43 (2.89, 14.35)

35

-0.97 (-1.64, -0.30)

7.77 (6.48, 9.07)

 p for trend

p = 0.93

p < 0.01

 

p = 0.01

  1. aORs adjusted odds ratios, aMean adjusted means, 95%CIs 95% confidence intervals
  2. *All models adjusted for maternal age, education, race/ethnicity, maternal pre-pregnancy BMI, and infant sex
  3. Preterm/non-preterm births
  4. SGA/non-SGA births