Nasal High Flow (HF) is a mode of ‘non-invasive’ respiratory support for preterm infants, with several potential modes of action, including generation of distending airway pressure, washout of the nasopharyngeal dead space, reduction of work of breathing, and heating and humidification of inspired gas. HF has several potential advantages over continuous positive airway pressure (CPAP), the most commonly applied form of non-invasive support, such as reduced nasal trauma, ease of use, and infant comfort, which has led to its rapid adoption into neonatal care. In recent years, HF has become a well-established and commonly applied treatment in neonatal care. This graphical abstract by Satyan Lakshminrusimha provides an overview of the benefits of high flow nasal cannula support in neonates. For more information, read this Review by Calum T. Roberts and Kate A. Hodgson
Maternal Health, Neonatology and Perinatology is an open access, peer-reviewed journal that considers articles on a broad range of topics related to the physiological and pathological conditions of women during preconceptional, perinatal, and postpartum periods; and of fetuses and newborn infants during and beyond their initial hospital stay. The topics within these subjects could include, but are not limited to, the etiology, epidemiology, clinical issues, diagnosis, prevention, treatment, and short and long-term outcomes.
Maternal Health, Neonatology and Perinatology is affiliated with the CROWN initiative, Core Outcomes in Women’s Health. CROWN is an international initiative, led by journal editors, to harmonise outcome reporting in women’s health research. We are coming together to address the widespread, unwarranted variation in reporting of outcomes. CROWN’s main aim is to encourage researchers to report core outcome sets for key conditions in women’s health.
About the Editors
Dr. Satyan Lakshminrusimha is Chair of Pediatrics at the University of California, Davis (USA). His research interests include persistent pulmonary hypertension of the newborn (PPHN), neonatal resuscitation and oxygen therapy.
Satyan is a is a prolific author having written and co-authored over 100 peer-reviewed manuscripts and several book chapters and a dedicated researcher. He is the recipient of National Institutes of Health, American Academy of Pediatrics and Canadian Paediatric Society grants in his role as the director of the Center for Developmental Biology of the Lung, where he is leading cutting edge research to transfer innovative discoveries from the laboratory to the bedside through clinical trials. He is interested in incorporating medical illustrations to enhance teaching medical professionals and parents.
Satyan is also a committed tenured professor of neonatal and pediatric medicine teaching the next generation of healthcare professionals earning him recognition as “Mentor of the Year 2016” from the Eastern Society for Pediatric Research in recognition of sustained excellence as an educator and mentor of medical students, pediatricians-in-training, and Pediatric faculty.
Dr. Irina Burd is Associate Professor of Gynecology and Obstetrics and Neurology at the Johns Hopkins University. She was recruited to the Johns Hopkins University to spearhead the development of the field of Fetal Medicine and Fetal Neurology, and is the founder and Director of the Johns Hopkins Integrated Research Center for Fetal Medicine, and Director of Maternal Fetal Medicine Fellowship.
Prior to coming to Johns Hopkins University, Dr. Burd earned Bachelor of Arts Degree from Rutgers University (Summa Cum Laude) and completed the combined Rutgers University/Princeton University MD/PhD Program. She completed her residency in Obstetrics and Gynecology at the Thomas Jefferson University and her fellowship in Maternal Fetal Medicine at the University of Pennsylvania. Dr. Burd developed research program studying the pathogenesis of fetal brain injury with exposure to intrauterine inflammation, and studies prenatally used neuroprotective agents to prevent cerebral palsy and a spectrum of neurobehavioral outcomes. She is studying how assessment of placental anatomy and function can be utilized for evaluation of fetal brain injury in utero, and guidance for administration of neuroprotective and immunomodulatory therapies. For her work and her unique area of expertise, Dr. Burd was selected as a Chair of NICHD Obstetrics and Maternal Fetal Medicine Subcommittee.
