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Table 2 Baseline characteristics of enrolled infants

From: Simplified antibiotic regimens for treating neonates and young infants with severe infections in the Democratic Republic of Congo: a comparative efficacy trial

Regimena   A B C D
Number of infants enrolled 148 139 148 139
Age at enrollment (days) Mean (SD) 17 (15) 17 (15) 17 (16) 20 (17)
<  7 days 54 (36.5%) 46 (33.1%) 55 (37.2%) 43 (30.9%)
≥ 7 days 94 (63.5%) 93 (66.9%) 93 (62.8%) 96 (69.1%)
Sex Male 75 (50.7%) 76 (54.7%) 70 (47.3%) 81 (58.3%)
Respiratory rate Mean (SD) 69 (19) 69 (19) 70 (20) 67 (19)
<  60 54 (36.5%) 47 (33.8%) 52 (35.1%) 57 (41.0%)
60–70 27 (18.2%) 21 (15.1%) 26 (17.6%) 16 (11.5%)
70–79 22 (14.9%) 33 (23.7%) 26 (17.6%) 32 (23.7%)
80–89 24 (16.2%) 20 (14.4%) 25 (16.9%) 19 (13.7%)
90–99 8 (5.4%) 9 (6.5%) 9 (6.1%) 8 (5.8%)
≥ 100 13 (8.8%) 9 (6.5%) 10 (6.8%) 7 (5.0%)
Temperature <  35.5 6 (4.1%) 8 (5.8%) 12 (8.1%) 12 (8.6%)
35.5–37.9 39 (26.4%) 47 (33.8%) 44 (29.7%) 33 (23.7%)
≥38.0–38.9 96 (64.9%) 70 (50.4%) 80 (54.1%) 76 (54.7%)
≥39.0 7 (4.7%) 14 (10.1%) 12 (8.1%) 18 (12.9%)
Poor feeding   23 (15.5%) 22 (15.8%) 26 (17.6%) 25 (18.0%)
Movement only on stimulation   3 (2.0%) 5 (3.6%) 3 (2.0%) 1 (0.7%)
Severe chest indrawing   33 (22.3%) 40 (28.8%) 32 (21.6%) 31 (22.3%)
Number of signs at enrollment 1 129 (87.2%) 120 (86.3%) 128 (86.5%) 120 (86.3%)
2 18 (12.2%) 18 (12.9%) 17 (11.5%) 16 (11.5%)
≥ 3 1 (0.7%) 1 (0.7%) 1 (0.7%) 3 (2.2%)
  1. aRegimen A: IM Gentamicin and IM Penicillin × 7 days; Regimen B: IM Gentamicin and oral amoxicillin × 7 days; Regimen C: IM Gentamicin × 7 days and IM Penicillin × 2 days then oral amoxicillin × 5 days; Regimen D: IM Gentamicin × 2 days and oral amoxicillin × 7 days