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Table 3 Crude linear regression coefficients showing the association between increases in continuous covariates on inflammatory markers

From: Maternal infections during pregnancy and offspring midlife inflammation

  Continuous variables/Geometric mean
  CRP IL-6 IL-10 TNF-α
Maternal pre-pregnancy BMI (kg/m2) 1.02 (1.00,1.03) 1.01 (1.00,1.02) 1.00 (1.00,1.01) 1.00 (0.97,1.02)
Maternal age at birth (years) 0.99 (0.98,0.99) 1.00 (0.99,1.00) 1.00 (1.00,1.00) 1.00 (0.99,1.01)
Parity     
 1 1.20 1.65 4.48 1.15
 2 1.12 1.60 4.39 1.22
 3 1.21 1.70 4.31 1.35
 4 0.91 1.68 4.35 1.17
 5+ 1.63 2.14 5.16 1.02
p-value for difference 0.06 0.01 0.09 0.56
Infection during pregnancy     
 No 1.20 1.68 4.44 1.22
 Yes 1.09 1.54 4.39 1.12
p-value for difference 0.18 0.06 0.53 0.28
Maternal civil status at conception     
 Married mother 1.03 1.60 4.39 1.19
 Unmarried mother 1.35 1.78 4.53 1.19
p-value for difference < 0.001 0.001 0.22 0.90
Tobacco smoking in pregnancy     
 No 1.13 1.63 4.39 1.22
 Yes 1.21 1.68 4.48 1.15
p-value for difference* 0.25 0.45 0.27 0.42
Child’s gender     
 Male 1.15 1.67 4.66 1.22
 Female 1.20 1.65 4.22 1.17
p-value for difference* 0.48 0.93 < 0.001 0.64
  1. Geometric means by categories of categorical covariates with corresponding p-values
  2. BMI body mass index, CRP C-reactive protein, IL-6 Interleukin-6, IL-10 Interleukin-10, TNF-α tumor necrosis factor-α, *p-values obtained using ANOVA