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Table 3 Per-protocol Analysis for Transcutaneous Hb at 4 months, Neonatal Jaundice and Polycythemia

From: Effects of timing of umbilical cord clamping on preventing early infancy anemia in low-risk Japanese term infants with planned breastfeeding: a randomized controlled trial

 

DCC

ECC

Relative risk (95% CI) / Mean difference (95% CI)

p value

Primary outcome

Spectrophotometric hemoglobin (SpHb) at 4 months

  (n = 127/DCC = 65,ECC = 62)

12.4

(0.8)

12.3

(0.7)

0.1

[−0.17, 0.35]

0.50

Secondary outcome

Anemia (SpHb < 11.0 g/dl) (n = 126/DCC = 64,ECC = 62)

1

(1.6)

0

(0.0)

1.0

[0.95, 1.02]

1.00

Neonatal jaundice

  Total serum bilirubin (TsB) (days 3-5)) a (n = 122/DCC = 63, ECC = 59)

12.8

(3.5)

12.1

(3.4)

0.7

[−0.55, 1.91]

0.27

  Over the excess level of transcutaneous bilirubin (TsB) b (n = 122/DCC = 63, ECC = 59)

6

(9.5)

4

(6.8)

1.4

[0.42, 4.73]

0.75

  Phototherapy c (n = 123/DCC = 63, ECC = 60)

7

(11.1)

4

(6.7)

1.7

[0.51, 5.40]

0.53

Hematocrit

  Hematocrit level (days 3-5) (%) a (n = 121/DCC = 62, ECC = 59)

57.2

(5.3)

52.5

(5.2)

4.6

[2.74, 6.53]

< 0.01*

  High hematocrit (Hct65%) (n = 121/DCC = 62, ECC = 59)

3

(4.6)

2

(3.0)

0.7

[0.10, 4.00]

0.68

  1. Data are presented as means (SD) or n (%)
  2. a The highest value among blood sampling conducted during days 3-5 were used
  3. b Over the excess value are based on Standard of Imura (1985)
  4. c Two (DCC = 1, ECC = 1) received phototherapy before met to standard of phototherapy for preventively.One (ECC = 1) did not received phototherapy even over level of the standard of phototherapy
  5. *p < .05