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Table 3 Length delta z-score from birth to subsequent age points by univariate linear regression analysisa

From: Antibiotic exposure and growth patterns in preterm, very low birth weight infants

  Length Delta Z-score at Age of Evaluation
~ 36 weeks ~ 2 months ~ 4 months ~ 6 months ~ 12 months
No. of infants 161 151 134 136 129
Gestational age 0.042 0.281b 0.329b 0.222b 0.251b
Delivery mode 0.159b,c 0.191b,c 0.118 0.052 0.073
Multiple gestation 0.015 0.076 0.061 0.042 0.086
Sex −0.069 −0.116 − 0.014 − 0.018 − 0.016
IUGR 0.253d 0.091 0.041 0.070 0.043
SGA 0.106 0.039 0.219b 0.283b 0.291b
CRIB-II score 0.263 0.244d 0.232d 0.130 0.118
Antibiotic exposure (days of therapy [DOT]) 0.021 −0.144 −0.092 −0.040 −0.077
BPD −0.120 −0.216d − 0.217d −0.138 − 0.130
PDA −0.153 − 0.171d −0.151 0.008 0.018
NEC −0.020 0.015 −0.002 0.073 0.003
Late-onset sepsis 0.244b −0.019 −0.056 − 0.049 0.007
TPN (total days) 0.033 −0.216d −0.159 − 0.073 −0.112
Caloric density (36 weeks, kcal/ounce) −0.070 0.003 0.012 0.015 0.081
  1. IUGR intrauterine growth restriction, SGA small for gestational age, CRIB Clinical Risk Index for Babies, BPD bronchopulmonary dysplasia, PDA patent ductus arteriosus, NEC necrotizing enterocolitis, TPN total parenteral nutrition
  2. aPearson correlation
  3. bPositive correlation, P < 0.05
  4. cPositive correlation with delivery by caesarean section
  5. dNegative correlation, P < 0.05