Antibiotic exposure and growth patterns in preterm, very low birth weight infants

Table 4 Weight ^a and length ^b delta z-scores from birth to subsequent age points by stepwise multivariate regression analysis^c

	Delta Weight z-Score^a
	~ 36 weeks	~ 2 months	~ 4 months	~ 6 months	~ 12 months
No. of infants	161	151	134	136	129
Length	0.359	0.476	0.562	0.599	0.606
Gestational age	–	0.346	0.242	0.272	0.316
IUGR	0.137	0.174	0.138	0.151	0.119
Total parenteral nutrition (total days)	−0.349	–	–	–	–
Delivery mode	0.174	–	–	–	–
Late-onset sepsis	–	−0.153	–	–	–
PDA	–	0.143	–	–	–
	Delta Length z-Score^b
	~ 36 weeks	~ 2 months	~ 4 months	~ 6 months	~ 12 months
Weight delta z-score	0.444	0.568	0.644	0.674	0.701
Late-onset sepsis	0.152	–	–	–	–

^aThe total days of parenteral nutrition showed a strong negative correlation with weight z-scores at 36 weeks’ postmenstrual age, while positive associations were seen with gestational age, length, and IUGR status. Antibiotic exposure was not significant at any time point. P-value was ≤0.05 for all displayed z-score values.
^bPositive associations were seen with the length delta z-score and late-onset sepsis (p < 0.05).
^cPearson correlation
IUGR intrauterine growth restriction, PDA patent ductus arteriosus

ISSN: 2054-958X