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Table 1 The differing diagnoses of neonatal hypoglycemia, and blood glucose analyser used in low resource settings

From: What are the barriers preventing the screening and management of neonatal hypoglycaemia in low-resource settings, and how can they be overcome?

Study

Country

Neonates

(n)

Diagnosis

Analyser

Risk factors

Bora et al., 2020 [26]

India

80

< 40 mg/dL (< 2.2mmol/L)

POC electrochemical, glucose oxidase

SGA

Ellis et al., 1996 [23]

Nepal

94

< 36 mg/dL (< 2.0 mmol/L)

POC electrochemical, reflectance meter and glucose oxidase

-

Gupta et al., 2022 [27]

India

629

< 45 mg/dL (< 2.2mmol/L)

in neonates > 24 h

 < 25 mg/dL (< 1.4mmol/L)

0 to 4 h

POC electrochemical

SGA, LGA, intrauterine growth-restriction, infants of diabetic mothers, late preterm (> 35 weeks)

Ibrahim et al., 2021 [31]

Pakistan

120

< 40 mg/dL (< 2.2mmol/L)

Laboratory

Preterm neonates (Mean gestational age was

32.3 + 6.37 weeks)

Mukunya et al., 2020 [62]

Uganda

1416

< 47 mg/dL (< 2.6mmol/L)

POC electrochemical

Delayed establishment of breastfeeding, < 3 days of age

Okomo et al., 2015 [24]

Gambia

4944

< 47 mg/dL (< 2.6mmol/L)

POC (analyser not specified)

-

Osier et al., 2003 [21]

Kenya

280

< 40 mg/dL (< 2.2mmol/L)

Glucose oxidase

Unable to establish breastfeeding, SGA

Pal et al., 2000 [61]

Nepal

578

Mild < 47 mg/dL (< 2.6mmol/L)

Moderate < 36 mg/dL (< 2.0 mmol/L)

Glucose oxidase

Postmaturity, SGA, delayed establishment of breastfeeding, small head size, haemoglobin > 210 g/l, raised maternal thyroid stimulating hormone

Sasidharan et al., 2004 [19]

India

604

< 40 mg/dL (< 2.2mmol/L)

Glucose oxidase

LBW, preterm, maternal diabetes, maternal oligohydramnios, pre-eclampsia, birth asphyxia, cold stress, hypothermia, delayed establishment of breastfeeding

  1. LBW: low birth weight; POC: point of care; SGA: small for gestational age